Alright, I'm assuming you're referring to the ammunition of the Gunblade, correct? The World's Blessing is no problem, it's just you have to have one Mark selected at a time during battles. The One Question and Spellbane however... Those both have to do with the actual rounds, since one dominates the body of it. Having both would be useless, as you have the drawback of an explosive round and not really "combat suited" materials inside your round. Spellbane's perk would act differently in a non-buckshot round. It wouldn't fire a wave of magic disruption materials, but would instead fire a concentrated round meant to wound magic users and disrupt spells from that. Again, not a buckshot. So it would actually do more damage than the actual Spellbane wound wise. One Question's perk would remain the same, more or less. Caliber changed might adjust a few very minor things, but it would still cause the much wanted explosions from each shot, staggering and sending shrapnel flying upon micro detonation. So I really comes down to your preference. What do you think?

Hm, it's a tough choice, what do you think, I want your opinion on how my gunblade should be buffed, cause remember, you added the hardlight mod to it, and it has to runes on it, one that increases the sharpness of it, and one that gives me control over lightning and lets me shoot lightning rounds

If you're going to be facing other magic users, and there's quite the bunch here, then I'd stick with Spellbane. Lightning rounds combined with this can make a deadly combo of dispelling enemy magic and them shocking them with your own. That being said, One Question is more versatile. Lightning rounds combined with staggering explosions that can dispatch groups of enemies quick is another good option, and not only restricted to one type of enemy. Personally, I'd go with One Question. Even though I face the jinx-flinging likes of you, Mage, Deth, and others, some people use shields or temporary armour that can be shattered from explosions, and then possibly disabled from a lightning shock.