In the alpha when an enemy would say immune (the enemy level is to high for you) it would take 1 damage per hit.
English
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really?
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Yep. Me and my friend spent an hour trying to kill the majors under the steps in cosmodrome. As you could imagine we were pissed when it only dropped 25 glimmer (we thought it was a boss.
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You can also kill them with sparrows.