Who would it be? I would personally pick Wheatley from Portal 2. While kinda a screw-up, he's frickin hilarious.
Edit: Just to clarify, I meant like an artificial intelligence, a machine.
Edit: Cortana seems to be the favorite here (no surprise).
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Edited by Bigger Masshole: 6/13/2015 10:32:55 PMGhost, MacMillan, or Sandman from COD. [spoiler]The reason for those guys is because you technically played as Roach, Soap, Price, Frost, Yuri, and Allen.[/spoiler]