Almost every bad guy in dbz was way stronger than anything thus far in destiny. Plus goku is the hero and he finds a solution even if death is required. I'm sure one kamehameha would take out any boss. Plus he could instant transmission the boss anywhere. I would say any relic is obsolete at this point since the creature would be sent out of the game world where its power resides . this is goku in his natural state. Imagine kao Ken, super sayian 1-4 , god goku. Come on dude. It's like saying superman vs destiny. Obviously superman wins. There is no kryptonite so the man of steel is free to soak up some rays and destroy everything.