Iceman can freeze his ass solid and then store him in a deep freezer in his garage. I can give you dozens of these. You do not have to kill him to beat him. Leech can suppress his powers and Deadpools cancer would eat him alive at which point you can put him in a block of concrete and deposit him in the ocean. Spiderman and incapacitate him quite easily and put him in a block of concrete and deposit him in the ocean. Hulk smash an so on and so on ...