Come on guys, really. Of the people on the list Deadpool has no competition. He's immortal. He also has a sword that negates healing abilities such as that of wolverines, making immortal people mortal.
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Iceman freezes him solid and puts him in a deep freezer in the basement. Spideman webs him up and puts him where ever he wants. Any number of characters can teleport or transport him to a lifeless planet and leave his ass there. So many characters can beat Deadpool, immortality does not mean you can beat everybody it just means you will not say dead.
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Well considering he killed off the entire marvel universe I'm pretty sure not many characters can actually beat him.
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How immortal is he? Things like guardian abilities and certain weapons turn people into dust could he survive something like that?
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Yes, he regenerates. Death has also forbidden him to die. Think of wolverines healing abilities on steroids.
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That's pretty cool I guess you have to like seal him to beat him. Maybe throw him in molten steel and let it solidify?
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He also can pull gadgets seemingly out of nowhere to aid him. He can also teleport, has super human reflexes, strength, speed, and the amazing ability to consistently break the 4th wall.
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Discussed below many times