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I'm understanding the question as the universe of Destiny, not literally. Like the universe of DBZ wouldn't have any guardians or a traveler, just like how the Destiny universe doesn't have any saiyans in it.
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The question seems to be goku enters destiny universe and fights everything in it....who wins. Answer not goku because he would refuse to fight. So goku is stronger but loses by way of forfeit because he is arrogant as -blam!-
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So its not even a fair question then. I don't even know why we need to argue about that. If this was no holds barred, Goku would win. We're talking about power here. Its like the stupid 'Who would win, Superman or Goku?'. I don't even know why this is worth arguing about >_>