Who would win?
I'm putting all my money on Goku.
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In this case though the destiny universe would be beat. Goku possesses high speed and the ability to destroy planets instantly. He also has a deterrent to the vex and their teleporting with his own teleportation. Goku would also have the ability to jump between universes. This ability was shown by ssj3 gotenks when they got stuck in the hyperbolic time chamber. The only way he could be beat is if he is tired out by a long battle but he could easily teleport away recover before anyone could catch him.