I've always thought about this while playing, what is the strongest weapon? We have weapons like ruinous effigy that can turn people into volatile spheres. Then we have touch of malice, which was made from the corpse of a hive god. And to top it all of we have bad juju, which is said to be capable of destroying existence itself. With weapons like these I really wonder how we haven't killed the witness already.
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Probably just cuz it's on my mind but maybe Whisper. Lore wise it gets stronger every time we kill something. Given that Eris became the most powerful hive god from killing savvy, what would have happened if you killed savvy with Whisper during the campaign...