Kotaku has just talked up this game a helluva lot, and it does sound pretty damn awesome.
The best part? Maybe they'll fix that -blam!-ing retarded Mass Effect dialogue system where Shephard says something similar to what you chose with unintended consequences, as opposed to the actual choice on the wheel. I reckon DE Human Revolution did a far better job of that.
On a side note, both this and BioShock Infinite are non-numbered threequels, but still have three 'I's in the subtitle.
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For once I'd love it if y character said "-blam!- you." when I select the -blam!- you option.