It happened to me today. For a lot of my nuke classes, we use government databases for tabulated information on neutron and photon cross sections. The websites that host these databases have all been shutdown. This means that I actually had to physically track down an ancient thing called a "book" to do my homework today. It didn't even give links to the studies/methodologies that were used to get the data.
Mark my words; someone is going to pay for this.
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My dad is a Senior Engineer for the US Army. He designs the Bradley tank and works on the simulations that are supposed to train the soldiers to use it. He didn't get furloughed, but more than half his team did. Many of the teams that he collaborates with were furloughed. So he goes to the office and can barely do any work and still gets paid.