It depends on: a) the game being played b) your hand shape and size c) the way you grip your mouse, and finally, d) your in-game sensitivity. Different mice sensors have different malfunction speeds, different levels of prediction, different levels of acceleration, and different lift-off-distances. The mice themselves have different textures, shapes, sizes, number of buttons and the cord properties vary tremendously! To put it simply, there is no best gaming mouse. If you're looking for a good mouse for a particular game you should consult some of the better players within that community.