We always hear COD fanboys and teenagers blindly regurgutate. "SHOOT CENTER OF MASS" Yeah, that works great when you are engaging a target at more than 20 meters with a proper rifle. But when it comes to personal self defense. If you have to use your weapon, And you have the opportunity to take a head-shot. DO IT. Handguns are not effective combat weapons. That's just the straight up truth. They shoot rounds that are smaller, lighter and slower than rounds fired out of a rifle platform. Unfortunately rifles do not make for an acceptable EDC defense weapon. So you will need to compensate for this. Handgun rounds to the center of mass. Can and will kill. But you will RARELY get a one shot incapacitate. It could literally take minutes for them to go down if they are on drugs, or just pumped up on adrenalin. If you have to use your weapon. It means that you are seconds away from death. When you are seconds from death at close range with an individual and you can take a head shot. Do it.