I tried being full Paragon once in a play through of ME3. My relationship with Liara was three games strong, until I decided to get some extra paragon points in a conversation with Cortez, I believe that's his name, the one who flew the drop ship. Before I even realized what was happening my Sheppard had apparently twitched sexualities. I then preceded to split the play through into one where Cortez and Shep were real Bros and another that I loaded from an earlier save on the same profile where Liara and Shep were still good. Besides maybe Jack, were there any situations where overly renegading produced the same result?