I could never quite figure which was more efficient in terms of killing boss's quicker, ammo efficiency vs DPS and if certain enemy types were damaged by one, more than the other, for example a boss having explosive resistance or something.
I want know what other people thought was best or should be best.
Note: Obviously when tested with base DPS all the same.
Edit: Didn't want to involve other weapons just to keep this simple.
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Using the Walker and Sepiks from Devil's Lair as an example, for Heavy Weapons the Machine Gun is the obvious choice. Rate of fire wins the day here, presuming you have the ammo. Primary/secondary weapons you would have to go Scout Rifle. Numerous people were able to solo the Walker in the Lair by finding a spot to avoid the cannons and pick at it's legs. This usually required a fair amount of range, making the SR the clear choice, again with it's rate of fire winning out over the Sniper.