Ah yes, the Hand Cannons. The experience of seeing your rounds pierce the cranium of your alien oppressors that only they can provide. Whose wielders tower over the filthy Scout, Pulse, and Auto Rifle plebians.
Come, my brethren, gather in this place and share your knowledge, tales, and advice to your fellow Marksmen.
I offer my own small piece of input: Acquiring Chain of Woe (exclusive to the mighty Hunter Mustard Rice (a topic for another day)), armor which increases Hand Cannon reload times, and a Hand Cannon itself that sports a 'melee hits reduce the reload time of this weapon' upgrade will result in all whom you come across fleeing back to the Darkness from whence they came.
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It's funny. In the beta, hand cannons just felt weak compared to everything else. Now that I have the full game I'm hesitant to switch to anything other than the hand cannon. The huge impact on them means "BLAM, headshot! BLAM, headshot! BLAM, headshot! BLAM, headshot!" and a big pile of dead Fallen. They're deadly accurate and they don't restrict your awareness of your surroundings as much as other guns because of zoom. Then to see there are Legendaries that allow the radar to stay active while zoomed? Mustard rice indeed...