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I have one and use it mostly for indies and other stuff that's good in short bursts. Remote play is impressive in terms of how well it actually functions (at least while on the same wifi network; I've never tried it while away from home). I have run some patrol missions, bounties, and less demanding story missions via remote play, but the precision on the sticks isn't as good as the dual shock 4, so more intense stuff would be tough, I'd think.
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I want one bad I have seen video's of it running using a dual shock 4 so its more comfortable people have even made stands \ clips for the Vita that clip on to the dual shock using coat hangers